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Paediatric chronic liver diseaseFew children have liver disease in early age below 1 year which is usually gradually progressive but signs or symptoms may be in late childhood.

Children with this kind of chronic liver disease have various manifestations like organomegaly (enlarged liver and spleen), jaundice, itching, neurological problems, acute viral hepatitis like presentation, and portal hypertension causing blood in vomiting or black tarry stool. Occasionally they present as rapid deterioration like acute liver failure.

Children with chronic liver disease require disease specific treatment at the appropriate time otherwise land up in liver failure and require liver transplantation.